for clarity what I meant by boundary conditions in my previous post is what these odds are being compared against for the AMA to give their advice. And my view is that they are comparing against now and not against the future, but my disappointment is that this isn’t made clear.The Pfizer advice from the AMA is based on the following: 3.1 clotting events per 100K for under 50's, 2.7/100K for 50-60, 1.5/100K for 60-80. Hence ATAGI decreed Pfizer preferred for u60's as that is where they deem the "acceptable" cutoff is, given the decreased frequency of blood clots with AZ after 60. But it's a sliding scale and you could still suffer clotting if you're over 60.